Clinical Need

Mitral Regurgitation

Mitral regurgitation (MR) occurs when the mitral valve (MV) fails to close properly, causing blood to leak back into the left atrium.

MR is the most common valvular heart disease, affecting about 1.7% of the population1.

Risk increased with age: 0.5% in 18 – 44 years old patients to 9.3% (1 in 10) in ages 75 and over.

Untreated MR can lead to decreased cardiac output, increased pulmonary congestion and heart failure.

Severe MR without intervention has a 1-year fatality rate of up to 57%.

Significant Unmet Need for Mitral Regurgitation Treatment

Existing patients in the US
0
New patients each year
0
Patients treated each year
0

References

  1. Otto, C. M., et al. 2020 ACC/AHA guideline for the management of patients with valvular heart disease… Circulation, 2021, 143(5), e72–e227.

  2. https://www.businessresearchinsights.com/market-reports/transcatheter-mitral-valve-repair-and-replacement-tmvr-market-108286